Little-scale’s extensive work with Sega sound synthesis brings this in-depth tutorial -

This tutorial is a step-by-step guide on how to make your very own 32KB Sega Master System cartridge. The cost is quite low (if you have a programmed EPROM or you are able to program your own) – I payed around AU$8 in parts for one of my carts as made in this tutorial.

These carts have been tested on a PAL SMS 1 and a PAL SMS 2.

The good news is that the cartridges use a re-programmable EPROM, provided that you have the appropriate facilities (EPROM programmer and EPROM eraser).

– How To Make a 32KB Sega Master System Cartridge