Lisa Laughly, aka Ninth Wave Designs, has done some absolutely stunning Moleskine art projects, including the Alchemy Notebook, seen here. Lisa incorporated her own modified versions of existing rune script, and then further obscured it by using a cipher wheel and grid (also built into the book). So the text has meaning, but good luck teasing it out — she also changes the rules of encipherment as she goes. The book even has pop-up features. I want to draw like this when I grow up.

Alchemy Notebook: Moleskine Pocket Sketchbook [via BibliOdyssey]