Suspended animation with hydrogen sulfide?

roth_mouse.jpg

It may smell like rotten eggs, but it turns out H2S may be able to slow down the chain of chemical degradation that causes death in cells that are deprived of oxygen. Biologist Mark Roth can supposedly take a lab rat, stop its heart with a dose of hydrogen sulfide, and bring it back to life an hour later just by turning off the gas. Quoting now from this article at CNN.com:

Scientists are starting to understand that death isn't caused by oxygen deprivation itself, but by a chain of damaging chemical reactions that are triggered by sharply dropping oxygen levels. The thing is, those reactions require the presence of some oxygen. Hydrogen sulfide takes the place of oxygen, preventing those reactions from taking place. No chain reaction, no cell death.

Roth has won a MacArthur grant for this work, so there's a better-than-average chance that it's more than just hype.


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Comments

Oldest comments listed first.

Posted by: Rolf Zullig on October 15, 2009 at 4:03 PM

Stop playing God

You cruel, sick shit! - Stop playing God! What gives you the right to experiment with living beings? You disgust me!


Posted by: angrier daily on October 15, 2009 at 4:21 PM

really?

Jesus really?
When your great grandchildren are exploring galaxies, or perhaps in ten years when you get hit by a car and put into suspended animation before getting your ass in a MRI, YOU'RE GOING TO FEEL FUCKING STUPID ABOUT THIS RESPONSE.
A. It isn't sound to accuse someone of "playing God" when you can't accurately define "God"
B. GO DIE and see if any of the future generations of enlightened immortal cyborgs even briefly notice.
Of course you'd have to be in some sort of afterlife to see your great grandkids chuckling from a spaceship. If that is the case it will indeed be I who feels foolish. However... science.


Posted by: fast_luck on October 15, 2009 at 4:19 PM

Yes, I agree!

This sick shit should stop it! What gives him the right to develop processes that could save untold HUMAN lives?


Posted by: Gilberti on October 15, 2009 at 6:05 PM

I know I'm getting ahead of myself here...

When we finally develop a "life-arresting" drug safe for humans, who would administer it? Would anesthesiologists be retrained in its use, or would there be a new medical technician solely to preform this procedure? How expensive would it be? How dangerous? How long can you keep a person in arrested life safely?


Posted by: Volkemon on October 15, 2009 at 6:50 PM

@Rolf Zullig-

Not to belittle your concept of God, but this seems a FAR cry from creating life out of 'dust' or other godlike activities. This is merely a 'pause button' in the timestream of a life. Not even rewind! Now THAT would be something bordering godlike...

It would be like calling a 10 year old that can drive a car around a field an automotive engineer.

Neat stuff. Thanks SMR!


Posted by: Andy L on October 15, 2009 at 6:59 PM

I want to double my total (remaining) lifespan by spending every other month in suspended animation. Finally now I know how!

I wonder how much hydrogen sulfide I can purchase before the end of the month.


Posted by: Jimbo on October 15, 2009 at 7:20 PM

Amazing stuff!

I work in the same field and know for quite a while now about this stuff. What the guys there discovered is simply amazing. The possibilities and potential of this are endless. People with heavy wounds could be saved until the damage is repaired by a surgeon, it tells us a lot about the cells functioning and will probably also impact the research on aging in itself!


Posted by: Anonymous on October 15, 2009 at 9:10 PM

I wonder how scalable something like this is for humans. Re-oxygenation in a creature the size and metabolism of a rat, I can see, would be a relatively rapid process. In something like a human however, I suspect a re-oxygenation process would be considerably slower, which opens up the possibility for those seized chemical reactions to initiate in these low oxygen environments. Likewise, would the process of administering the hydrogen sulfide induce death in the transitional low oxygen stage?


Posted by: Jesse on October 16, 2009 at 1:03 AM

I remember hearing about this QUITE some time ago, and I still find it just amazing.

I'd love to see this put to use in some way.
(Though I certainly don't want to ever "need" it)


Posted by: Harley on October 16, 2009 at 4:15 AM

Generic tech news blog

So this is just another generic vague-tech-science-gee-whiz news blog now? Or are they going to release a new Instructables: How to Kill Your Own Mouse with an Arduino, RepRap, and Cory Doctorow.


Posted by: Anonymous on October 18, 2009 at 4:13 PM

You all are missing the real point here: Hydrogen Sulfide is what puts the SMELLY in FARTS. Yes, this is a fart chamber. You huff the biggest longest fart of all time, and time stops. Great. Yay science!


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